It is used to treat chronic, severe pain. Hydromorphone works on the brain to increase the ability to tolerate pain. Hydromorphone controlled-release works by gradually releasing the medication into the body to help control pain that requires the prolonged or continuous use of an opioid pain killer. Hydromorphone is a strong pain reliever that can be fatal if it is taken by someone for whom it has not been prescribed.
Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here. Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor.
Do not stop taking this medication without consulting your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
Nonmedicinal ingredients: colloidal silicon dioxide, dibutyl sebacate, ethyl cellulose, hydroxypropylmethyl cellulose, magnesium stearate, and microcrystalline cellulose; capsule shell: gelatin, titanium dioxide, and yellow iron oxide.
Nonmedicinal ingredients: colloidal silicon dioxide, dibutyl sebacate, ethyl cellulose, hydroxypropylmethyl cellulose, magnesium stearate, and microcrystalline cellulose; capsule shell: gelatin, iron oxide, and titanium dioxide. For people who are not currently taking other opioid pain medications or are taking low doses of weak opioid medications, the usual adult dose of hydromorphone controlled-release capsules is 3 mg every 12 hours.
For people who are receiving other formulations of hydromorphone or other opioid medications, the dose depends on the dose of these medications that you are currently taking.
Your doctor will determine the dose that is appropriate for you. Your doctor can adjust your dose every 48 hours until a dose that controls your pain with tolerable side effects is reached. Your daily dose should be taken in two equally divided doses every 12 hours. Swallow hydromorphone controlled-release capsules whole, or open them and sprinkle the contents on cold, soft food. Rinse your mouth with liquid to make sure that you have swallowed the entire contents of the capsule.
Do not chew, crush, dissolve, or break the contents of the capsule, as this could result in too much hydromorphone being released rapidly and could be fatal. It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule.
If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature in a dry place and keep it out of the reach of children.
Do not dispose of medications in wastewater e. Ask your pharmacist how to dispose of medications that are no longer needed or have expired. It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice. Store this medication at room temperature in a dry place and keep it out of the reach of children. Do not dispose of medications in wastewater e. Ask your pharmacist how to dispose of medications that are no longer needed or have expired. Nonmedicinal ingredients: colloidal silicon dioxide, dibutyl sebacate, ethyl cellulose, hydroxypropylmethyl cellulose, magnesium stearate, and microcrystalline cellulose; capsule shell: gelatin, titanium dioxide, and yellow iron oxide.
Nonmedicinal ingredients: colloidal silicon dioxide, dibutyl sebacate, ethyl cellulose, hydroxypropylmethyl cellulose, magnesium stearate, and microcrystalline cellulose; capsule shell: gelatin, iron oxide, and titanium dioxide. Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses.
Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects. Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.
Stop taking the medication and seek immediate medical attention if any of the following occur:. Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Before you begin taking a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health.
These factors may affect how you should take this medication. Accidental use: Accidental ingestion or use of as little as one dose of hydromorphone by someone for whom it has not been prescribed can lead to a fatal overdose. Children are especially at risk. Keep this medication out of sight and reach of children. Alcohol and other medications that cause drowsiness: Do not combine this medication with alcohol or other medications e.
Asthma and other respiratory conditions: Hydromorphone may cause increased breathing difficulty for people having an acute asthma attack, or those with chronic obstructive pulmonary disease chronic bronchitis, emphysema or other conditions that affect breathing. If you have asthma or another breathing disorder, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Dependence: As with other opioid medications narcotics , this medication may become habit-forming if taken for long periods of time. There is a problem with information submitted for this request. Sign up for free, and stay up-to-date on research advancements, health tips and current health topics, like COVID, plus expert advice on managing your health. Error Email field is required. Error Include a valid email address. To provide you with the most relevant and helpful information and to understand which information is beneficial, we may combine your e-mail and website usage information with other information we have about you.
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Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Hydromorphone may cause serious or life-threatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is increased.
Your doctor will monitor you carefully during your treatment. Tell your doctor if you have slowed breathing or have or have ever had asthma. Your doctor will probably tell you not to take hydromorphone. Also tell your doctor if you have or have ever had lung disease such as chronic obstructive pulmonary disease a group of diseases that affect the lungs and airways , a head injury, a brain tumor, or any condition that increases the pressure in your brain, or kyphoscoliosis curving of the spine that may cause breathing problems.
The risk that you will develop breathing problems may be higher if you are an older adult, or are weakened or malnourished due to disease. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: slowed breathing, long pauses between breaths, or shortness of breath. Taking certain medications during your treatment with hydromorphone may increase the risk that you will develop serious or life-threatening breathing problems, sedation, or coma.
Tell your doctor if you are taking or plan to take any of the following medications: benzodiazepines such as alprazolam Xanax , chlordiazepoxide Librium , clonazepam Klonopin , diazepam Diastat, Valium , estazolam, flurazepam, lorazepam Ativan , oxazepam, temazepam Restoril , and triazolam Halcion ; medications for mental illness or nausea; muscle relaxants; other narcotic pain medications; sedatives; sleeping pills; or tranquilizers.
Your doctor may need to change the doses of your medications and will monitor you carefully. If you use hydromorphone with any of these medications and you develop any of the following symptoms, call your doctor immediately or seek emergency medical care: unusual dizziness, lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness.
Be sure that your caregiver or family members know which symptoms may be serious so they can call the doctor or emergency medical care if you are unable to seek treatment on your own. Drinking alcohol, taking prescription or nonprescription medications that contain alcohol, or using street drugs during your treatment with hydromorphone increases the risk that you will experience serious, life-threatening side effects.
Do not drink alcohol, take prescription or nonprescription medications that contain alcohol, or use street drugs during your treatment. Swallow the extended-release tablets whole. Do not split, chew, dissolve, or crush them. If you swallow broken, chewed, crushed, or dissolved tablets you may receive too much hydromorphone at once instead of receiving the medication slowly over time.
This may cause serious breathing problems or death. Do not allow anyone else to take your medication. Hydromorphone may harm or cause death to other people who take your medication, especially children. Keep hydromorphone in a safe place so that no one else can take it accidentally or on purpose.
Be especially careful to keep hydromorphone out of the reach of children. Keep track of how many tablets or how much liquid is left so you will know if any medication is missing. Dispose of unwanted or no longer needed tablets, extended-release tablets, and liquid by flushing the medication down the toilet. Tell your doctor if you are pregnant or plan to become pregnant. If you take hydromorphone regularly during your pregnancy, your baby may experience life-threatening withdrawal symptoms after birth.
Tell your baby's doctor right away if your baby experiences any of the following symptoms: irritability, hyperactivity, abnormal sleep, high-pitched cry, uncontrollable shaking of a part of the body, vomiting, diarrhea, or failure to gain weight.
Your doctor or pharmacist will give you the manufacturer's patient information sheet Medication Guide when you begin your treatment with hydromorphone and each time you fill your prescription.
Read the information carefully and ask your doctor or pharmacist if you have any questions. Hydromorphone is used to relieve pain. Hydromorphone extended-release tablets are used to relieve severe pain in people who are expected to need pain medication around the clock for a long time and who cannot be treated with other medications.
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