How does cholestasis in pregnancy affect the gallbladder




















It is thought that pregnancy hormones, and especially the additional estrogen , may affect the proper functioning of the gallbladder and the liver. The prevalence of cholestasis of pregnancy is not known.

One estimate suggests that it affects 1 to 2 pregnancies in every 1, in the U. Other figures suggest that up to 1 in 50 women may develop it, depending on the population. As well as intense itching, the mother may have some problems with absorbing fat-soluble vitamins, which are vitamins A, D, E and K.

However, within a few days after giving birth, the problems should resolve. There will not usually be any further liver problems. For the fetus, there is a significantly higher risk of preterm birth if the mother has cholestasis of pregnancy, although the reasons are unclear. An infant who is born preterm may have breathing difficulties if the lungs are not yet fully developed. If the mother has too much bile acid, this can be passed onto the fetus.

The neonate also has a higher risk of inhaling meconium during childbirth, resulting in breathing difficulties. Doctors often induce labor early if the mother has cholestasis of pregnancy, because of the potentially serious complications for the baby.

Research suggests that cholestasis of pregnancy may increase the risk of metabolic disorders, such as obesity and cardiovascular disorders, when the child reaches adulthood. A non-stress test may be ordered to check how often the fetus moves in a given period, and the fetal heartbeat in relation to body movements is also measured.

Induced labor is often recommended at about 38 weeks. If cholestasis is severe, induction may occur earlier. Preeclampsia is a condition that can occur during pregnancy when a woman's blood pressure rises sharply.

It is usually detected during routine checks…. Jaundice is a condition that causes skin and the whites of the eyes to turn yellow. Jaundice usually occurs because of an underlying condition with…. Amniocentesis is a test that detects chromosomal abnormalities in the fetus. A sample of amniotic fluid is taken from the amniotic sac.

The test may…. Sleep disorders among pregnant women are associated with early birth. A diagnosis of cholestasis can be made by doing a complete medical history, physical examination, and blood tests that evaluate liver function, bile acids, and bilirubin. Cholestasis may increase the risks for fetal distress , preterm birth, or stillbirth.

The treatment goals for cholestasis of pregnancy are to relieve itching. Make sure you speak with your healthcare provider before taking any medications or supplements.

Some treatment options include:. Treatment for cholestasis of pregnancy needs to be determined by your physician, who will take the following criteria into consideration:.

In the past, this medication was readily used to treat this condition, but some studies have shown that Cholestyramine may not be as effective as other treatments and potentially has some adverse side effects such as blocking essential vitamins like Vitamin K a vitamin that is already deficient in women with cholestasis.

It is nearly impossible to know whether a woman will experience cholestasis in future pregnancies. If you plan on getting pregnant again, talk to your healthcare provider about steps you can take to promote a healthy pregnancy, or if there are any ways to prevent ICP. Want to Know More? Compiled using information from the following sources: 1. Gary, et al, Ch. Cholestasis of Pregnancy. What causes cholestasis of pregnancy?

What are the symptoms? A fetal arrhythmia is an irregular heart rate — too fast, too slow, or otherwise outside the norm. It's often benign. Postpartum diarrhea after a C-section is normal. Sharing our experiences of pregnancy and infant loss can help us heal. Health Conditions Discover Plan Connect. Gallbladder purpose Pregnancy effects Symptoms Talk to your doctor Treatments Next steps Intro Your gallbladder may be a relatively small organ, but it can cause big trouble during your pregnancy.

Knowing the symptoms can help you get medical attention before it get worse. How does the gallbladder work? How can pregnancy affect gallbladder functioning? Symptoms of gallbladder problems during pregnancy. Cholestasis of pregnancy can cause very specific symptoms. Talking to your doctor about symptoms. Treatments for gallbladder problems during pregnancy. Next steps. Parenthood Pregnancy Pregnancy Health. Relieving Gallbladder Pain Naturally.

Gallbladder Disease. Read this next. What Does a Contracted Gallbladder Mean? Medically reviewed by Judith Marcin, M. Medically reviewed by Alana Biggers, M.



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